Genicular Artery Embolization (GAE)
Genicular artery embolization (GAE) is a minimally invasive, image-guided option for selected patients with chronic knee pain from osteoarthritis — designed to reduce inflammation-related pain without surgery.
- Treats
- Chronic knee pain related to osteoarthritis in selected patients
- Common symptoms
- Persistent knee pain, stiffness, reduced mobility
- Typical setting
- Outpatient — most patients return home the same day
- Recovery
- Many patients return to light activity quickly; results vary
- Candidates
- Patients evaluated for knee osteoarthritis-related pain who prefer a non-surgical option
About this condition
Knee osteoarthritis develops when the cartilage and soft tissues in the knee gradually wear down, often causing inflammation, pain, and stiffness.
Many patients try physical therapy, anti-inflammatory medications, lifestyle changes, or steroid injections before considering knee replacement surgery.
Genicular artery embolization (GAE) is a minimally invasive option that targets the abnormal blood vessels associated with inflammation in the knee.
How Genicular Artery Embolization (GAE) works
GAE is performed by an interventional radiologist. A thin catheter is guided through a small access point — often in the upper thigh — to the genicular arteries that feed the inflamed tissue around the knee.
Tiny embolic particles are released to reduce blood flow to those abnormal vessels, which can help reduce inflammation-related pain.
GAE does not replace the knee joint and does not reverse arthritis itself. It targets inflammation-related pain.
Benefits and tradeoffs
No procedure is right for every patient. Below are general benefits and considerations to discuss with your physician.
- Minimally invasivePerformed through a small access point — no large incision.
- OutpatientMost patients return home the same day.
- Knee-preservingGAE does not replace the knee joint.
- Option before knee replacement for some patientsFor selected candidates, GAE may be considered before or alongside other treatments.
- Targets inflammation-related painImage-guided embolization focuses on abnormal vessels feeding inflamed tissue.
- ConsiderationsGAE is not a cure for arthritis and is not appropriate for every patient. A physician evaluation is required.
Who may be a candidate?
The list below is general — it is not a diagnosis. A Beacon IR Clinic physician will review your history and imaging during a consultation.
- Chronic knee pain related to osteoarthritis
- Pain that has not responded well to conservative treatments
- Patients who prefer to delay or avoid knee replacement when possible
- Selected patients after physician review of imaging and history
Take the next step
Tell us about your symptoms and we will help schedule an appropriate consultation.
Schedule ConsultationBefore, during, after, and recovery
A general guide. Your physician will share the plan specific to your case.
Before
- Initial consultation, in person or virtually
- Review of imaging and prior treatments
- Discussion of expected goals and limitations
During
- Performed in an outpatient setting under conscious sedation
- Image-guided catheter through a small access point
- Targeted embolization of selected genicular arteries
After
- Short observation period
- Discharge home the same day for most patients
- Written post-procedure instructions and follow-up plan
Recovery
- Many patients return to light activity quickly
- Pain relief is gradual and varies by patient
- Follow-up to assess response
Frequently asked questions
What is genicular artery embolization?
GAE is a minimally invasive, image-guided procedure that reduces blood flow to abnormal vessels associated with inflammation in the knee.
Is GAE an alternative to knee replacement?
For selected patients, GAE may be considered before or alongside other treatments. Whether it is appropriate depends on your individual case and physician evaluation.
Who is a candidate for GAE?
Patients with chronic knee pain from osteoarthritis whose symptoms have not responded well to conservative measures, and who are evaluated by a physician.
How soon can patients return to normal activity?
Many patients return to light activity quickly. Pain relief often develops gradually and varies by patient.
Does GAE treat arthritis itself or pain from inflammation?
GAE targets inflammation-related pain by reducing blood flow to abnormal vessels in the affected tissue. It does not reverse the underlying arthritis.
Related conditions & treatments
Varicose Vein Treatment
Beacon IR Clinic provides evaluation and minimally invasive treatment for varicose veins and venous insufficiency — including radiofrequency ablation and sclerotherapy for appropriate candidates.
Men's HealthProstate Artery Embolization (PAE)
Prostate artery embolization (PAE) is a minimally invasive, image-guided treatment for selected patients with symptoms of benign prostatic hyperplasia (BPH) — designed to relieve urinary symptoms without traditional prostate surgery.
Helpful resources
Genicular Artery Embolization (GAE) guide
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